People use a wide range of nutrients, amino acids, botanicals and sleep-support ingredients. The appropriate option depends on whether the goal is focus, calm, sleep or nutritional support.

Evidence varies by ingredient and population. Avoid products that promise to prevent dementia, reverse cognitive decline or produce guaranteed memory improvement.

Potential interactions can be important. Ask the clinician or pharmacist managing your medication before combining sedating supplements with prescription drugs.

Regular physical activity, adequate sleep, balanced nutrition, cardiovascular risk management, social engagement and appropriate medical care are foundational.